Interstitial Lung Disease in Common Variable Immunodeficiency

Intravenous Immunoglobulin Monotherapy for Granulomatous Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency

Common variable immunodeficiency (CVID) is a heterogeneous subset of immunodeficiency disorders. Recurrent bacterial infection is the main feature of CVID, but various non-infectious complications can occur. A 42-year-old woman presented with cough and abnormal chest X-ray shadows. Laboratory tests showed remarkable hypogammaglobulinemia. Computed tomography revealed multiple consolidation and ...

Common Variable Immunodeficiency and Peripheral Lung Nodule

Introduction Cryptococcus neoformans is an encapsulated yeast fi rst isolated by Busse in 1894 from the tibia of a 31-year-old woman [1]. Lungs are considered the initial site of almost all cryptoccocal infections, and the second clinically more relevant after central nervous system. The pattern of pulmonary disease is extremely variable, ranging from asymptomatic saprophytic airway colonizatio...

British Lung Foundation/United Kingdom Primary Immunodeficiency Network Consensus Statement on the Definition, Diagnosis, and Management of Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders.

A proportion of people living with common variable immunodeficiency disorders develop granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a consensus statement on the definition, diagnosis, and management of GLILD. All UK specialist centers were contacted and relevant physicians were invited to take part in a 3-round online Delphi process. Responses were graded as S...

Common variable immunodeficiency misdiagnosed as Crohn Disease

Background Common variable immunodeficiency (CVID) is one of the most common primary immunodeficiency in adults and is characterized by defective antibody production, low levels of serum immunoglobulins and increased susceptibility to infection. About 20% of developed different gastrointestinal pathology. But also the pathology of the gastrointestinal tract in patients with CVID showed a wide s...

Hodgkin's disease and common variable immunodeficiency.